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Bruno Pradines Selected Research

Quinine (Quinson)

12/2020Amide Tethered 4-Aminoquinoline-naphthalimide Hybrids: A New Class of Possible Dual Function Antiplasmodials.
9/2020Antimalarial drugs inhibit the replication of SARS-CoV-2: An in vitro evaluation.
6/2017Absence of association between polymorphisms in the K13 gene and the presence of Plasmodium falciparum parasites at day 3 after treatment with artemisinin derivatives in Senegal.
1/2017The end of a dogma: the safety of doxycycline use in young children for malaria treatment.
2/2016Macrolides and associated antibiotics based on similar mechanism of action like lincosamides in malaria.
11/2015Tetracyclines in malaria.
9/2015Absence of association between Plasmodium falciparum small sub-unit ribosomal RNA gene mutations and in vitro decreased susceptibility to doxycycline.
6/2013In vitro susceptibility to quinine and microsatellite variations of the Plasmodium falciparum Na+/H+ exchanger transporter (Pfnhe-1) gene in 393 isolates from Dakar, Senegal.
3/2013Plasmodium falciparum susceptibility to anti-malarial drugs in Dakar, Senegal, in 2010: an ex vivo and drug resistance molecular markers study.
12/2011Differential association of Plasmodium falciparum Na+/H+ exchanger polymorphism and quinine responses in field- and culture-adapted isolates of Plasmodium falciparum.
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Bruno Pradines Research Topics

Disease

69Malaria
04/2021 - 04/2003
15Falciparum Malaria (Plasmodium falciparum Malaria)
08/2021 - 07/2008
10COVID-19
01/2022 - 06/2020
6Infections
01/2022 - 10/2007
6Cerebral Malaria
08/2017 - 01/2012
5Neoplasms (Cancer)
08/2020 - 12/2005
3Reinfection
04/2022 - 05/2012
3Vector Borne Diseases
11/2016 - 11/2015
2Sepsis (Septicemia)
08/2013 - 01/2012
1Thrombocytopenia (Thrombopenia)
01/2021
1Coinfection
10/2020
1Superinfection
10/2020
1Premature Birth (Birth, Premature)
12/2018
1Dental Enamel Hypoplasia
01/2017
1Rickettsia Infections
01/2017
1Q Fever (Fever, Q)
01/2017
1Overweight
09/2016
1Bites and Stings (Sting)
03/2016
1Parasitemia
04/2014
1Breast Neoplasms (Breast Cancer)
12/2011
1Glioblastoma (Glioblastoma Multiforme)
04/2010
1Fever (Fevers)
07/2008

Drug/Important Bio-Agent (IBA)

25Antimalarials (Antimalarial Agents)IBA
04/2021 - 04/2003
21Pharmaceutical PreparationsIBA
11/2021 - 12/2005
17Quinine (Quinson)FDA Link
12/2020 - 06/2009
16artemisinin (artemisinine)IBA
08/2021 - 08/2006
15Doxycycline (Periostat)FDA LinkGeneric
01/2022 - 02/2009
12Chloroquine (Aralen)FDA LinkGeneric
12/2020 - 04/2003
10artenimol (dihydroartemisinin)IBA
01/2020 - 06/2009
8ArtesunateIBA
10/2020 - 06/2013
6Methylene Blue (Methylthioninium Chloride)FDA Link
07/2021 - 04/2013
6Mefloquine (Lariam)FDA LinkGeneric
10/2020 - 06/2009
6piperaquineIBA
01/2020 - 11/2013
6Atorvastatin (Lipitor)FDA Link
05/2014 - 06/2009
5Antiviral Agents (Antivirals)IBA
01/2022 - 09/2020
5pyrimethamine drug combination fanasil (Fansidar)FDA Link
12/2020 - 01/2017
4desethylamodiaquineIBA
12/2020 - 06/2009
3Amodiaquine (Camoquin)FDA Link
11/2021 - 03/2013
3Hydroxychloroquine (Plaquenil)FDA LinkGeneric
11/2021 - 09/2020
3ferroquineIBA
09/2020 - 07/2006
3pyronaridineIBA
09/2020 - 05/2014
3Drug CombinationsIBA
01/2020 - 06/2011
3Anti-Bacterial Agents (Antibiotics)IBA
11/2016 - 09/2015
3LumefantrineFDA Link
05/2014 - 06/2009
3Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
08/2013 - 06/2009
3AntigensIBA
01/2013 - 06/2006
2Azithromycin (Zithromax)FDA LinkGeneric
11/2021 - 02/2016
2Biomarkers (Surrogate Marker)IBA
07/2021 - 10/2007
2stephanineIBA
08/2020 - 09/2017
2Codon (Codons)IBA
01/2020 - 08/2006
2proguanil drug combination atovaquone (malarone)FDA Link
01/2020 - 05/2012
2Cytochromes b (Cytochrome b)IBA
01/2020 - 05/2012
2TetracyclinesIBA
11/2016 - 11/2015
2MacrolidesIBA
11/2016 - 02/2016
2L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
01/2016 - 03/2013
2Atovaquone (Mepron)FDA Link
05/2014 - 06/2009
2Neuroprotective AgentsIBA
08/2013 - 01/2012
2Folic Acid AntagonistsIBA
09/2011 - 08/2006
2quinolineIBA
09/2008 - 01/2008
2Proteins (Proteins, Gene)FDA Link
07/2008 - 06/2006
2QuinolinesIBA
01/2008 - 08/2006
2Subfamily B ATP Binding Cassette TransporterIBA
08/2006 - 12/2005
1VaccinesIBA
04/2022
1favipiravirIBA
11/2021
1clofoctolIBA
11/2021
1Heparin (Liquaemin)FDA LinkGeneric
11/2021
1Clofazimine (Lamprene)FDA Link
11/2021
1Ivermectin (Mectizan)FDA Link
11/2021
1nitazoxanide (NTZ)FDA Link
11/2021
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
04/2021
1CytokinesIBA
10/2020
1AlkaloidsIBA
08/2020
1Aurora KinasesIBA
08/2020
1TabletsIBA
01/2020
1ArtemetherFDA Link
06/2017
1InsecticidesIBA
03/2016
1LincosamidesIBA
02/2016
1Clindamycin (Cleocin)FDA LinkGeneric
02/2016
1Merozoite Surface Protein 1 (MSA1)IBA
01/2016
1ArtemisininsIBA
01/2016
1Vitamin K 3 (Menadione)FDA Link
01/2016
1plasmodioneIBA
01/2016
1Lumefantrine Drug Combination Artemether (Coartem)FDA Link
12/2015
1Tetracycline (Achromycin)FDA LinkGeneric
11/2015
1chloroquine diphosphateFDA LinkGeneric
12/2014
1AlbuminsIBA
04/2014
1Blood Proteins (Serum Proteins)IBA
04/2014
1OxidesIBA
04/2014
1LigandsIBA
12/2011
1Cisplatin (Platino)FDA LinkGeneric
12/2011
1AntibodiesIBA
07/2008

Therapy/Procedure

19Therapeutics
08/2021 - 11/2010
15Chemoprevention
01/2017 - 06/2006
1Hand Hygiene
01/2022
1Oral Administration
11/2021
1Critical Care (Surgical Intensive Care)
01/2021
1Prenatal Care (Care, Prenatal)
12/2018
1Aftercare (After-Treatment)
01/2018
1Contraindications
01/2017
1Drug Therapy (Chemotherapy)
11/2016